Roland Jonsson CV

 

Roland Jonsson
 

 

ROLAND JONSSON DMD, PhD
The Broegelmann Chair in Immunology
Director, Bergen Research School in Inflammation (BRSI)
Deputy head (research), the Gade Institute
Consultant, Department of Rheumatology, Haukeland University Hospital

 

 

Personal

Born March 23, 1950, at Gunnarskog, Värmland, Sweden

Citizen of Sweden; Languages: Swedish, English

E-mail: roland.jonsson@gades.uib.no

http://www.uib.no/Broegelmann/

http://www.uib.no/Broegelmann/brsi/index.html

Educational Background

1969 Chemistry (20 points/credits = 6 months), Basic course, University of Göteborg

1970 - 1974 Odontology D.D.S./D.M.D., University of Göteborg

1975 - 1976 Pathology, Oto-rhino-laryngology, Faculty of Medicine, University of Göteborg

1983 Ph.D. (odont. dr.), University of Göteborg

Thesis title: Oral manifestations of systemic lupus erythematosus

Professional Record

1975 - 1988 Resident Oral Diagnosis/Medicine and Oral Pathology - Specialist Training and Immunopathological and Immunohistochemical Diagnostic Service, University of Göteborg, Sweden

1977 - 1991 Consultant in Oral Medicine, Departments of Dermatology and Rheumatology, Sahlgrenska University Hospital, Göteborg, Sweden

1988 - 1990 Visiting Scientist/Research Associate Professor (Immunology), Department of Microbiology, University of Alabama at Birmingham, AL, USA (Prof Jiri Mestecky and Prof William J. Koopman)

1990 - 1991 Associate Professor in Oral Diagnostics, University of Göteborg, Sweden

1991 - Head, Broegelmann Research Laboratory, University of Bergen, Norway and Professor of Medicine (Immunology), [from 2004 - The Broegelmann Chair in Immunology], The Gade Institute, University of Bergen, Norway

1995 - Clinical Consultant in Oral Medicine, Departments of Rheumatology and Otolaryngology/Head and Neck Surgery, Haukeland University Hospital, Bergen, Norway

2005 - Vice-chairman, The Gade Institute, University of Bergen, Norway

Scientific Bibliography and Main Activities

Bibliometric data: ISI - H-index = 40; > 6300 citations: worldwide no. 3 in Sjögren's syndrome and no.1 in sialadenitis research according to biomedexperts.com.

≈ 250 peer-reviewed articles, with contributions in journals such as Nature Genetics (2), Lancet (2), Trends in Immunology (1), Proceedings National Academy of Science (USA) (1), Arthritis & Rheumatism (11), American Journal of Pathology (1), European Journal of Immunology (3), Journal of Immunology (1), Journal of Infectious Diseases (2), Laboratory Investigation (5), Infection and Immunity (2) and > 15 textbook chapters, in the following areas of research: Sjögren´s syndrome; Immunology of experimental autoimmunity (arthritis and sialadenitis); Apoptosis and chronic inflammation; Mucosal immunobiology and pathology; Oral medicine/pathology

Training: Supervision in immunology (autoimmunity, immunopathology, mucosal immunity): doctoral theses finalized (11 primary supervisor, 18 secondary supervisor), ongoing (4); master theses finalized (6); special reports by medical students finalized (6); postdoctoral fellows (4), ongoing (3).

Hosted: ≈ 25 visiting international scientists / guest researchers / postdoctoral research fellows (1993 -)

Principal Investigator: on research grants supported by the Swedish Medical Research Council, the Norwegian Medical Research Council, the North Atlantic Treaty Organization (NATO), EU BioMed II and the Marie Curie Training programs.

Organizer: (Chairman or Member of Organizing Committee) of Scientific Meetings: "First Meeting of International Association of Oral Pathologists", Göteborg, 1981; Workshop in Autoimmunity, Bergen, 1993; Chairman, Organizing Committee of "International Conference on Immunopathology of Mucous Membranes and Exocrine Glands", Bergen, 1997; "The 19th European Workshop for Rheumatology Research", Oslo, 1999; "International Conference on Autoantibodies and Autoimmunity", Oslo, 1999; "The 100-Year Anniversary of Henrik Sjögren", Jönköping, 1999; Int Adv Committee "The VII International Symposium on Sjögren´s syndrome", Venice, 1999; Member, International Conference on Immunology (ICI-2001) Sponsor Committee Advisory Group; Organizer NOS-M seminar: "Mucosal Immunity - Role in Local Defense and Immunopathology", Oslo, 2001; Principal Organizer of Satellite Meeting to the ICI-2001: B cells & Autoimmunity: New Concepts & Therapeutic Perspectives, Bergen, 2001; President of the 33rd Scandinavian Society of Immunology Meeting, Bergen, 2002; Member of the Scientific Committee of the 8th World Congress of Inflammation, Copenhagen 2007; Member of the Scientific Committee of the 2nd European Congress of Immunology, Berlin 2009.

Major known current and previous sources of funding

1996 - 1999 Coordinator of EU BioMed II, No: BMH4-CT96-0595: "Sjögren's syndrome - a strategy for clarifying the disease process that underlies a chronic disorder of the mucous membranes"; NOK 3 280 000 (≈ $ 656 000)

1997 - 1999 Norwegian Medical Research Council: "Chronic inflammatory connective tissue disease in women"; NOK 2 340 000 (≈ $ 468 000)

1998 - 2000 EU BioMed II Shared Cost Project No: BMH4-CT98-3489: "The genetics of systemic lupus erythematosus and Sjögren's syndrome: A strategy for identification of susceptibility genes in two related disorders", (Coordinated by Prof. U. Gyllensten & M. Alarcon-Riquélme, Uppsala University, Sweden); NOK 9 720 000 (≈ $ 1 944 000); Bergen share: NOK 622 500 (≈ $ 124 500)

2000 - 2002 NATO Collaborative Linkage grant (Moscow, Oklahoma City, Bergen): NOK 240 000 (≈ $ 48 000)

2000 - 2005 EU Marie Curie Training Site at University of Bergen No: QLK2-1999-51079; NOK 1 200 000 (≈ $ 240 000)

2001 - 2002 EU Accompanying Measure Contract No: QLK2-CT-2001-30115 NOK 600 000 (≈ $ 120 000)

2005 - 2009 Coordinator of a EU Marie Curie Early Stage Training project No: MEST-CT-2004-514483 (including 9 PhD trainee fellowships); NOK 14 000 000 (≈ $ 2 400 000)

2005 - 2009 Coordinator of the Strategic Research Program at Helse Bergen, Haukeland University Hospital, Bergen, Norway, "Immunology with a Special Focus on Mucosa Associated Autoimmune Diseases and Tumor Biology"; NOK 3 800 000 (≈ $ 760 000)

2007 - 2010 Coordinator of the Western Norway Regional Health Authorities project "Sjögren's Syndrome - Molecular and Clinical Markers for Diagnosis and Progression"; NOK 2 250 000 (≈ $ 450 000)

2009 - 2012 Coordinator of the Norwegian Research Council GLOBVAC project "Mucosal vaccination against autoimmune diseases"; NOK 7 938 000 (≈ $ 1 300 000)

Honors and Awards

1985 Research Fellowship in Rheumatology (3 years), Swedish Medical Research Council

1986 Göteborg Dental Society Award for Young Scientists, Sweden

1993 The Zendium prize, Norway

1997 Presentation of the Annual Pindborg Lecture, 23. SFOPOM Meeting, Göteborg, Sweden

1999 State-of-the-Art-Lecture on "Sjögren´s syndrome", The 63rd Annual Meeting of American College of Rheumatology, Boston, USA (Recorded on CD-ROM) (≈10.000 delegates)

2000 - Appointed "Research Affiliate in Immunology", The Forsyth Institute - Harvard, Boston, USA

2001 State-of-the-Art-Lecture on "Oral Manifestations of Rheumatic Diseases", The 65th Annual Meeting of American College of Rheumatology, San Fransisco, USA (≈8.000 delegates)

2003 - Appointed "Adjunct Member" and from 03/05 "Affiliated Member" of the Arthritis and Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, USA

2005 Awarded "The Research Group of the Year", Faculty of Medicine, University of Bergen, Norway

2006 Elected member of the Norwegian Academy of Science and Letters

2009 Western Norway Regional Health Authority Research Prize (National)

2009 European Federation of Immunological Societies - Immunology Letters Lecture Award (International)

2010 Distinguished Scientist Award - International Association of Dental Research (International)

Committees and Boards

1999 - Member Medical and Scientific Advisory Board of the Sjögren´s Syndrome Foundation, USA

1999 - Member National Committee for IUIS, The Norwegian Academy of Science and Letters

2005 - Chairman Scandinavian Foundation for Immunology

2007 - 2010 President of the Scandinavian Society for Immunology (>1000 members)

2009 - Member Board of Directors European Federation of Immunological Societies (EFIS)

Membership of Professional Organizations

1991 British Society of Immunology

1991 Scandinavian Society of Immunology

1992 American College of Rheumatology

1997 Norwegian Rheumatology Society

2000 Henry Kunkel Society

2006 Norwegian Academy of Science and Letters

Editorial and Review Activities

Editor-in-Chief: Scandinavian Journal of Immunology (1999 - present)

Editorial Board Member/Advisory Editor: Scandinavian Journal of Immunology (1995 - 1999); European Journal of Oral Sciences (1999 - 2005); Scandinavian Journal of Rheumatology (2000 - present); Arthritis & Rheumatism (2000 - 2004 [4-year assignments]); Current Rheumatology Reviews (2004 - present); Up-to-date Rheumatology (2005 - present); Annals of Rheumatic Diseases (2008 - ).

Ad hoc reviews for scientific journals: AIDS Research and Human Retroviruses, APMIS, Acta Odontologica Scandinavica, Acta Opthalmologica Scandinavica, Advances in Dental Research, American Journal of Pathology, Annals of the Rheumatic Diseases, Archives of Oral Biology, Arthritis Research & Therapy, Arthritis & Rheumatism, Autoimmunity, Blood, Clinical and Experimental Immunology, Clinical and Experimental Rheumatology, European Archives of Oto-Rhino-Laryngology, European Journal of Oral Sciences, Gut, International Immunopharmacology, Journal of Clinical Investigation, Journal of Dental Research, Journal of Immunology, Journal of Oral Pathology & Medicine, Journal of Proteome Research, Journal of Rheumatology, Laboratory Animals, Lancet, Nature Clinical Practice in Rheumatology, Nature Reviews Rheumatology, Oral Diseases, Otolaryngology - Head and Neck Surgery, Proceedings National Academy of Science (USA), Rheumatology, Scandinavian Journal of Caring Sciences, Scandinavian Journal of Dental Research, Scandinavian Journal of Immunology, Scandinavian Journal of Plastic and Reconstructive Surgery, Scandinavian Journal of Rheumatology, The Immunologist, UpToDate - Rheumatology, Vaccine.

Grant Reviewer - Advisory Committees (Member and/or Leader):

  • The Research Council of Norway - Member of study section/peer review committee for "Clinical Research" 1994 - 98; Chairman of the "Clinical Research" study section 1998 - 2001; Expert evaluator 2004, 2005;

  • The European Commission, Brussels, Belgium: Biomed II - 1995 and 1997; Chairman subpanel "Chronic Inflammatory Diseases" 1997; Quality of Life and Management of Living Resources - Ageing 1999, Chronic/Degenerative Diseases 2000, Accompanying Measures 2000, Ageing 2001. Midterm Review - Ageing 2001.

  • The Foundation Health and Rehabilitation (Norway) - Board member 1997 - 2004;

  • Basic Research Foundation, The Israel Academy of Sciences and Humanities, 1992;

  • The Italian Ministry for University and Research 1998;

  • Fond zur Förderung der wissenschaftlichen Forschung (Austria) 1998;

  • Foundation Pour La Recherche Médicale (France) 2001;

  • Arthritis Research Campaign (UK) 2002

  • The Academy of Finland - International Expert Evaluator 2005

  • The Danish Research Agency - International Expert Evaluator 2005, 2006

  • Sahlgrenska Akademi 2007

  • The Sjögren's Syndrome Foundation, USA 2008, 2009, 2010

  • VINNOVA - Innovationer för framtidens hälsa (Sweden) 2008, 2009

  • Royal Swedish Academy of Sciences 2008

  • European Science Foundation 2009

  • Welcome Trust (UK) 2010

Evaluation of professorship status: immunology (7), molecular genetics (1), medicine (1), rheumatology (1), oral biology (2), oral pathology (1), oral medicine (1), oral immunology (1)

Evaluation of doctoral (PhD) thesis (opponent and/or committee-chairman): medical sciences (18), odontology (10)

Recent Invitations as Speaker/Key-note Lecturer

1999 Glasgow, Scotland (>6.000 delegates); Boston, USA; Zürich, Switzerland; Venice, Italy; Turku, Finland; Gainesville, USA; Bethesda, USA

2001 Ventura, CA, USA; Copenhagen, Denmark; San Fransisco, USA

2002 Geneva, Switzerland; Ettal, Germany; Kanazawa, Japan; Tromsø, Norway; Regensburg, Germany; London, UK

2003 Budapest, Hungary; Rhodes, Greece; Zürich, Switzerland; Miyazaki, Japan

2004 Berlin, Germany; Beijing, China; Göteborg, Sweden; Jeju, South Korea; Birmingham, AL, USA; Paris, France

2005 Brisbane, Australia; Sydney, Australia; Adelaide, Australia

2006 Kvitfjell, Norway; Washington DC, USA; Reykjavik, Iceland; Sorrento, Italy

2007 Uppsala, Sweden; Turku, Finland; Rio de Janeiro, Brazil; Boston, USA

2008 Zürich, Switzerland; Paris, France; Stockholm, Sweden; Berlin, Germany; Antalaya, Turkey

2009 Brest, France; Kyrenia, Cyprus;

2010 Vienna, Austria; Tallinn, Estonia; Göteborg, Sweden; London, UK

2011 Izmir, Turkey; Changsa City, China; Athens, Greece

Peer-Reviewed Publications 2006 - [1-39]

1. Szyszko EA, Skarstein K, Jonsson R, Brokstad KA: Distinct phenotypes of plasma cells in spleen and bone marrow of autoimmune NOD.B10.H2b mice. Autoimmunity 2011.

2. Szyszko EA, Brun JG, Skarstein K, Peck AB, Jonsson R, Brokstad KA: Phenotypic diversity of peripheral blood plasma cells in primary Sjögren's syndrome. Scand J Immunol 2011, 73:18-28.

3. Szyszko EA, Brokstad KA, Oijordsbakken G, Jonsson MV, Jonsson R, Skarstein K: Salivary glands of primary Sjögren's syndrome patients express factors vital for plasma cell survival. Arthritis Res Ther 2011, 13:R2.

4. Seror R, Ravaud P, Mariette X, Bootsma H, Theander E, Hansen A, Ramos-Casals M, Dorner T, Bombardieri S, Hachulla E et al: EULAR Sjögren's Syndrome Patient Reported Index (ESSPRI): development of a consensus patient index for primary Sjögren's syndrome. Ann Rheum Dis 2011.

5. Hovden AO, Karlsen M, Jonsson R, Aarstad HJ, Appel S: Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses. BMC Immunol 2011, 12:2.

6. Vogelsang P, Brun JG, Oijordsbakken G, Skarstein K, Jonsson R, Appel S: Levels of plasmacytoid dendritic cells and type-2 myeloid dendritic cells are reduced in peripheral blood of patients with primary Sjögren's syndrome. Ann Rheum Dis 2010, 69:1235-1238.

7. Seror R, Mariette X, Bowman S, Baron G, Gottenberg JE, Boostma H, Theander E, Tzioufas A, Vitali C, Ravaud P: Accurate detection of changes in disease activity in primary Sjögren's syndrome by the European League Against Rheumatism Sjögren's Syndrome Disease Activity Index. Arthritis Care Res (Hoboken) 2010, 62:551-558.

8. Nordmark G, Kristjansdottir G, Theander E, Appel S, Eriksson P, Vasaitis L, Kvarnstrom M, Delaleu N, Lundmark P, Lundmark A et al: Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome. Genes Immun 2010.

9. Cobb BL, Fei Y, Jonsson R, Bolstad AI, Brun JG, Rischmueller M, Lester SE, Witte T, Illei G, Brennan M et al: Genetic association between methyl-CpG binding protein 2 (MECP2) and primary Sjögren's syndrome. Ann Rheum Dis 2010, 69:1731-1732.

10. Carracedo S, Lu N, Popova SN, Jonsson R, Eckes B, Gullberg D: The fibroblast integrin alpha11beta1 is induced in a mechanosensitive manner involving activin A and regulates myofibroblast differentiation. J Biol Chem 2010, 285:10434-10445.

11. Vogelsang P, Hovden AO, Jonsson R, Appel S: Levels of dendritic cell populations and regulatory T cells vary significantly between two commonly used mouse strains. Scand J Immunol 2009, 70:541-546.

12. Reksten TR, Jonsson MV, Szyszko EA, Brun JG, Jonsson R, Brokstad KA: Cytokine and autoantibody profiling related to histopathological features in primary Sjögren's syndrome. Rheumatology (Oxford) 2009, 48:1102-1106.

13. Nordmark G, Kristjansdottir G, Theander E, Eriksson P, Brun JG, Wang C, Padyukov L, Truedsson L, Alm G, Eloranta ML et al: Additive effects of the major risk alleles of IRF5 and STAT4 in primary Sjögren's syndrome. Genes Immun 2009, 10:68-76.

14. Illes A, Varoczy L, Papp G, Wilson PC, Alex P, Jonsson R, Kovacs T, Konttinen YT, Zeher M, Nakken B et al: Aspects of B-cell non-Hodgkin's lymphoma development: a transition from immune-reactivity to malignancy. Scand J Immunol 2009, 69:387-400.

15. Hjelmervik TO, Jonsson R, Bolstad AI: The minor salivary gland proteome in Sjögren's syndrome. Oral Dis 2009, 15:342-353.

16. Capra JD, Froland SS, Harboe M, Jonsson R, Ljunggren HG, Wigzell H: Professor emeritus Jacob B. Natvig, one of the founders of Scandinavian journal of immunology, turns 75. Scand J Immunol 2009, 70:503-504.

17. Szodoray P, Nakken B, Gaal J, Jonsson R, Szegedi A, Zold E, Szegedi G, Brun JG, Gesztelyi R, Zeher M et al: The complex role of vitamin D in autoimmune diseases. Scand J Immunol 2008, 68:261-269.

18. Jonsson R, Ljunggren HG, Natvig JB, Orn A: Goran Moller 1936-2008. Scand J Immunol 2008, 68:113.

19. Jonsson R: The Nobel prize in physiology or medicine for 2008. Scand J Immunol 2008, 68:553.

20. Isaksen K, Jonsson R, Omdal R: Anti-CD20 treatment in primary Sjögren's syndrome. Scand J Immunol 2008, 68:554-564.

21. Haldorsen K, Moen K, Jacobsen H, Jonsson R, Brun JG: Exocrine function in primary Sjögren syndrome: natural course and prognostic factors. Ann Rheum Dis 2008, 67:949-954.

22. Delaleu N, Madureira AC, Immervoll H, Jonsson R: Inhibition of experimental Sjögren's syndrome through immunization with HSP60 and its peptide amino acids 437-460. Arthritis Rheum 2008, 58:2318-2328.

23. Delaleu N, Jonsson R: Altered fractalkine cleavage results in an organ-specific 17 kDa fractalkine fragment in salivary glands of NOD mice. Arthritis Res Ther 2008, 10:114.

24. Delaleu N, Jonsson MV, Appel S, Jonsson R: New concepts in the pathogenesis of Sjögren's syndrome. Rheum Dis Clin North Am 2008, 34:833-845, vii.

25. Delaleu N, Immervoll H, Cornelius J, Jonsson R: Biomarker profiles in serum and saliva of experimental Sjögren's syndrome: associations with specific autoimmune manifestations. Arthritis Res Ther 2008, 10:R22.

26. von Bultzingslowen I, Sollecito TP, Fox PC, Daniels T, Jonsson R, Lockhart PB, Wray D, Brennan MT, Carrozzo M, Gandera B et al: Salivary dysfunction associated with systemic diseases: systematic review and clinical management recommendations. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007, 103 Suppl:S57 e51-15.

27. Thangarajh M, Masterman T, Hillert J, Moerk S, Jonsson R: A proliferation-inducing ligand (APRIL) is expressed by astrocytes and is increased in multiple sclerosis. Scand J Immunol 2007, 65:92-98.

28. Jonsson R, Nginamau E, Szyszko E, Brokstad KA: Role of B cells in Sjögren's syndrome--from benign lymphoproliferation to overt malignancy. Front Biosci 2007, 12:2159-2170.

29. Jonsson R, Bolstad AI, Brokstad KA, Brun JG: Sjögren's syndrome--a plethora of clinical and immunological phenotypes with a complex genetic background. Ann N Y Acad Sci 2007, 1108:433-447.

30. Jonsson MV, Skarstein K, Jonsson R, Brun JG: Serological implications of germinal center-like structures in primary Sjögren's syndrome. J Rheumatol 2007, 34:2044-2049.

31. Jonsson MV, Delaleu N, Jonsson R: Animal models of Sjögren's syndrome. Clin Rev Allergy Immunol 2007, 32:215-224.

32. Hjelmervik TO, Lindqvist AK, Petersen K, Johannesson M, Stavrum AK, Johansson A, Jonsson R, Holmdahl R, Bolstad AI: The influence of the NOD Nss1/Idd5 loci on sialadenitis and gene expression in salivary glands of congenic mice. Arthritis Res Ther 2007, 9:R99.

33. Thangarajh M, Masterman T, Helgeland L, Rot U, Jonsson MV, Eide GE, Pirskanen R, Hillert J, Jonsson R: The thymus is a source of B-cell-survival factors-APRIL and BAFF-in myasthenia gravis. J Neuroimmunol 2006, 178:161-166.

34. Szodoray P, Jonsson R, Brun JG, Zeher M: Polymyalgia rheumatica in primary Sjögren's syndrome. Rheumatol Int 2006, 26:401-403.

35. Szodoray P, Alex P, Frank MB, Turner M, Turner S, Knowlton N, Cadwell C, Dozmorov I, Tang Y, Wilson PC et al: A genome-scale assessment of peripheral blood B-cell molecular homeostasis in patients with rheumatoid arthritis. Rheumatology (Oxford) 2006, 45:1466-1476.

36. Moen K, Brun JG, Valen M, Skartveit L, Eribe EK, Olsen I, Jonsson R: Synovial inflammation in active rheumatoid arthritis and psoriatic arthritis facilitates trapping of a variety of oral bacterial DNAs. Clin Exp Rheumatol 2006, 24:656-663.

37. Mittelholzer CM, Brokstad KA, Pauksens K, Jonsson R, Brytting M, Linde A: Human cell lines used in a micro neutralization test for measuring influenza-neutralizing antibodies. Scand J Immunol 2006, 63:257-263.

38. Holen E, Bjorge OA, Jonsson R: Dietary nucleotides and human immune cells. II. Modulation of PBMC growth and cytokine secretion. Nutrition 2006, 22:90-96.

39. Centola M, Frank MB, Bolstad AI, Alex P, Szanto A, Zeher M, Hjelmervik TO, Jonsson R, Nakken B, Szegedi G et al: Genome-scale assessment of molecular pathology in systemic autoimmune diseases using microarray technology: a potential breakthrough diagnostic and individualized therapy-design tool. Scand J Immunol 2006, 64:236-242.

 

Peer-Reviewed Publications (in press & in revision)

  1. Appel S, Le Hellard S, Bruland O, Brun JG, Omdal R, Kristjasndottir G, Theander E, Nordmark G, Kvarnström M, Eriksson P, Rönnblom L, Wahren Herlenius M, Jonsson R: Potential association of muscarinic receptor 3 gene variants with primary Sjögren's syndrome. Ann Rheum Dis, in press.

  2. Bolstad AI, Le Hellard S, Kristjasndottir G, Nordmark G, Brun JG, Omdal R, Theander E, Kvarnström M, Wahren Herlenius M, Eriksson P, Rönnblom L, Jonsson R: Association between lymphotoxin alpha genetic variants and primary Sjögren's syndrome in Scandinavian samples. PLoS One, revision requested

  3. Delaleu N, Nguyen CQ, Peck AB, Jonsson R: Sjögren's syndrome: studying the disease in mice. Arthritis Res Ther, in press.

  4. Nginamau ES, Mæhle BO, Jonsson R. An experimental protocol for the fractionation and 2DE separation of HeLa and A253 cell lysates suitable for the identification of the individual antigenic proteome in Sjögren´s syndrome. Autoimmity, revision requested.

  5. Theander E, Vasaitis L, Baecklund E, Nordmark G, Warfvinge G, Liedholm R, Brokstad KA, Jonsson R, Jonsson MV. Lymphoid organisation in Labial Salivary Gland Biopsies is a Possible Predictor for Development of Malignant Lymphoma in Primary Sjögren's Syndrome. Ann Rheum Dis, in press.