Andrea Olschewski, Univ. Prof. Dr.
Professor of Experimental Anaesthesiology
Dean for Doctoral Studies at the MedicalUniversity of Graz
Date of birth: October 5, 1966
Place of birth: Debrecen, Hungary
1986-1992 Study of Medicine, MD, University of Debrecen, Ungarn
1999 PhD thesis in Neurophysiology, University of Giessen, Germany
1993-1999 Resident, Department of Anesthesiology, University of Giessen, Germany
1999 Board certification in Anesthesiology
1999-2005 Senior physician, Department of Anesthesiology, University of Giessen
2000-2002 Postdoctoral Fellow of the German Research Foundation (DFG) at the University of Minnesota, Minneapolis, MN, USA
2002 Habilitation in Anesthesiology
2002-2005 Associate Professor, Department of Anesthesiology, University of Giessen, Germany
2002-2005 Deputy Director for academic affairs, Department of Anesthesiology, University of Giessen, Germany
2005 Board certification in Pain Therapy
2006-present Full Professor of Experimental Anesthesiology, Medical University of Graz, Austria
2010-present Director, Ludwig-Boltzmann Institute for Lung Vascular Research, Graz
Externally funded national and international projects (2006-2011): German Research Foundation (DFG), European Union 6th Framework; Austrian National Bank (OenB); Ludwig Boltzmann Society
2008-present Dean for Doctoral Studies, Medical University of Graz, Austria
Invited referee for > 20 scientific journals and > 10 funding organizations
Honors and Awards
1999 Fresenius Award of the German Society of Anesthesiologists
2000 Fellowship of the German Research Foundation (DFG)
2001 Cournand and Comroe Young Investigator Prize of the American Heart Association
2002 Research Award of the JustusLiebigUniversity of Giessen
2006 Research Award of the Austrian Society of Pneumology
2007 Galenus von Pergamon Prize
2009 Manfred Specker Medaille Award of the German Society of Anesthesiologists for Mentoring
Selection of publications
Olschewski A. 2011. Blocking potassium channels: a new principle for treating restenosis? Cardiovasc Res 89(2):255-7
Olschewski A. 2010. Targeting TASK-1 channels as a therapeutic approach. Adv Exp Med Biol 661:459-73
Auer-Grumbach M, Olschewski A, Papić L, Kremer H, McEntagart ME, Uhrig S, Fischer C, Fröhlich E, Bálint Z, Tang B, Strohmaier H, Lochmüller H, Schlotter-Weigel B, Senderek J, Krebs A, Dick KJ, Petty R, Longman C, Anderson NE, Padberg GW, Schelhaas HJ, van Ravenswaaij-Arts CM, Pieber TR, Crosby AH, Guelly C. 2010. Alterations in the ankyrin domain of TRPV4 cause congenital distal SMA, scapuloperoneal SMA and HMSN2C. Nature Genet 42: 160-164.
Tang B, Li Y, Nagaraj C, Morty RE, Gabor S, Stacher E, Voswinckel R, Weissmann N, Leithner K, Olschewski H, Olschewski A. 2009. Endothelin-1 inhibits background two-pore domain channel task-1 in primary human pulmonary artery smooth muscle cells. Am J Respir Cell Mol Biol 41: 476-483.
Weissmann N, Dietrich A, Fuchs B, Kalwa H, Ay M, Dumitrascu R, Olschewski A, Mederos y Schnitzler M, Ghofrani HA, Schermuly RT, Pinkenburg O, Seeger W, Grimminger F, Gudermann F. 2007. Classical transient receptor potential channel 6 (TRPC6) is essential for hypoxic pulmonary vasoconstriction and alveolar gas exchange. Proc Natl Acad Sci U S A (PNAS) 103: 19093-19098.
Weir EK, Olschewski A. 2006. Role of ion channels in acute and chronic response of pulmonary vasculature to hypoxia. Cardiovasc Res 71: 630-641.
Hong Z, Hong F, Olschewski A, Cabrera JA, Varghese A, Nelson D, Weir EK. 2006. Role of store-operated calcium channels and calcium sensitization in normoxic contraction of the ductus arteriosus. Circulation 114: 1372-1379.
Olschewski A, Li Y, Tang B, Hänze J, Eul B, Bohle RM, Wilhelm J, Morty R, Brau ME, Weir EK, Kwapiszewska G, Klepetko W, Seeger W, Olschewski H. 2006. Impact of TASK-1 in human pulmonary artery smooth muscle cells. Circ Res 98: 1072-1080.
Olschewski A, Hong Z, Peterson DA, Nelson DP, Porter VA, Weir EK. 2004. Opposite effects of redox status on membrane potential, cytosolic calcium and tone in pulmonary arteries and ductus arteriosus. Am J Physiol Lung Cell Mol Physiol 286:L15-22
Hong Z, Weir EK, Nelson DP, Olschewski A. 2004. Sub-acute hypoxia decreases Kv channel expression and function in pulmonary artery myocytes. Am J Resp Cell Mol Biol 31:1-7
Olschewski A, Hempelmann G, Vogel W, Safronov B. 1998. Blockade of Na+ and K+ currents by local anesthetics in the dorsal horn neurons of the spinal cord Anesthesiology 88:172-180
Olschewski A, Bräu ME, Olschewski H, Hempelmann G, Vogel W. 1996. ATP-dependent potassium channel in rat cardiomyocytes is blocked by lidocaine. – Possible impact on the antiarrhythmic action of lidocaine Circulation 93:656-659