Dr. Debora Grosskopf-Kroiher
Date of birth: 22. Feb. 1961
Center for Molecular Medicine Cologne (CMMC)
Interdisciplinary Program Molecular Medicine (IPMM)
Robert-Koch-Str. 21, 50931 Cologne, Germany
Phone: + 49 221 478 55 52
Fax: + 49 221 478 4833
Scientific Coordinator and Head of the Management Office
of the Center for Molecular Medicine Cologne (CMMC) and
Program Manager of the Interdisciplinary Program Molecular Medicine (IPMM) at the University of Cologne.
Since 2001 Dr. Debora Grosskopf-Kroiher has held the positions of Scientific Coordinator and Head of the Management Office at the CMMC – an autonomous center within both the Faculty of Medicine and the Faculty of Mathematics and Natural Sciences at the University of Cologne (UoC). D.G.-K. is not only responsible for ensuring the scientific, administrative and structural coordination and management of the CMMC, but is also highly involved in a range of public outreach and educational programs. In addition, D.G.-K. also played an instrumental role in the planning and construction of the new building at the CMMC, where she was responsible for ensuring that all building measures and operational issues were successfully implemented during the six-year construction period.
Interdisciplinary Program Molecular Medicine at the University of Cologne
Since 2003 D.G.-K. has held the position of Program Manager of the Interdisciplinary Program Molecular Medicine (IPMM) – a novel graduate program that was established by the Faculty of Medicine and the Faculty of Mathematics and Natural Sciences at the UoC. The IPMM supports and trains outstanding young physicians (after 2nd state examination or equivalent) and postgraduate natural scientists, thereby providing young medics and researchers with relevant and timely high-quality training to better promote their careers in the field of biomedical research. After completion of the IPMM curriculum and successful defense of the PhD thesis, the degree of “Doktor der Naturwissenschaftlichen Medizin” (Dr. nat. med.) is jointly conferred. So far, 30 doctoral students have successfully completed this program and over 60 doctoral students are currently enrolled.
Since 2008 D.G.-K. has been responsible for selection and enrolment of all PhD students at the Faculty of Medicine and works closely together with the Dean’s Office on the development and implementation of additional new graduate and postgraduate programs.
Graduate Education and Research Activities
Before embarking on a career in science management, D.G.-K. was an active researcher in the field of plant molecular biology.
From 1982 to 1987 D.G.-K. studied Biology at the University of Heidelberg, Germany and was awarded the degree “Diploma-Biology” (equivalent to a MSc.) for which she spent a year abroad as a “DAAD” exchange student in the group of Dr. Ian Scott at the Department of Botany & Microbiology, University College of Wales, Aberystwyth, Great Britain.
From 1988 to 1992 she actively pursued her doctoral research in the area of signal transduction in plant cells under the supervision of Prof. Thomas Boller at the Friedrich Miescher Institute (FMI), Basel, Switzerland and obtained her PhD degree from the University of Basel in 1992.
From 1992 to 1994 she worked as a postdoctoral fellow on mRNA editing in mitochondria of plants in the group of Prof. Mike Mulligan at the Department of Development & Cell Biology, University of California, Irvine, USA. This research activity was supported by a combined fellowship from the Swiss National Fund and the Ciba Geigy Foundation.
In 1995 D.G.-K. returned to Germany to pursue her second postdoctoral position in the group of Prof. Klaus Palme at the Max Planck Institute for Plant Breeding in Cologne. Until 2001 her research project focused on the development of a transcriptional activation system for regulated gene expression in transgenic plants and was partly supported by fellowships from the State North Rhine Westphalia and by the Max Planck Society.
Moore I, Gälweiler L, Grosskopf DG, Schell J & Palme K (1998) A transcription activation system for regulated gene expression in transgenic plants. Proc. Natl. Acad.Sci. USA 95: 376-381.
Grosskopf DG & Palme K (1998) Turning on transgenics: an effective OFF/ON gene expression system in transgenic plants. PIP NewsLetter 15: 17-18.
Grosskopf DG & Mulligan RM (1996) Developmental and tissue specificity of RNA editing in mitochondria of suspension-cultured maize cells and maize seedlings. Current Genetics 29: 556-563.
Spanu P, Grosskopf DG, Felix G & Boller T (1994) The turnover of 1-aminocyclopropane carboxylate synthase in tomato cells is dependent on protein phosphorylation and dephosphorylation. Plant Physiology 106: 529-535.
Grosskopf DG, Felix G & Boller T (1991) Protein phosphorylation is involved in the recognition of pathogen-derived signals by the plant cell. NATO ASI Series Vol 56: 477-481.
Grosskopf DG, Felix G & Boller T (1991) A yeast-derived glycopeptide elicitor and chitosan or digitonin differentially induced ethylene biosynthesis, phenylalanine ammonia-lyase and callose formation in suspension-cultured tomato cells. J. Plant Physiol. 138: 741-746.
Felix G, Grosskopf DG, Regenass & Boller T (1991) Rapid changes of protein phosphorylation are involved in transduction of the elicitor signal in plant cells. Proc. Natl. Acad.Sci. USA 88: 8831-8834.
Felix G, Grosskopf DG, Regenass M, Basse CW & Boller T (1991) Elicitor-induced ethylene biosynthesis in tomato cell. Plant Physiol. 97: 19-25.
Grosskopf DG, Felix G & Boller T (1990) K-252a inhibits the response of tomato cells to fungal elicitors in vivo and their microsomal protein kinase in vitro. FEBS Lett. 275: 177-180.
Grosskopf DG & Scott I (1988) Amyloplast development in etiolated and ethylene treated pea epicotyls. Planta 175: 425-431.
Taylor JE, Grosskopf DG, McGaw BA, Horgan R & Scott I (1988) Apical location of 1-aminocyclopropane-1-carboxylic acid. Planta 174: 112-114.
Grosskopf DG & Kroiher M (1988) Gradients in plastid and mitochondrial DNA synthesis in Funaria protonemata: Visualization by bromodeoxyuridine immunohistochemistry. Protoplasma 147: 1-4.