ROBERT ADAM HARRIS CV

CURRICULUM VITAE

1. Name: ROBERT ADAM HARRIS

2. Date and place of Birth: 12^th May 1966, Harpenden, UK

3. Address: Centre for Molecular Medicine L8:04, Karolinska Hospital

4. Contact: Tel: +46 8 5177 6561E-mail:Robert.Harris@ki.se

5. Professional Education 1987 BSc (Hons) Biology – Upper Second Class Portsmouth Polytechnic, UK

1991 PhD ’Haemolymph proteins and the snail immune response’ University College London, UK

6. Professional Record

1991-1991 University College London MRC Post-doctoral fellow

1991-1994 London School of Hygiene MRC Post-doctoral fellow

& Tropical Medicine

1994-1996 Karolinska Institutet Wellcome Trust Travel Fellow

1996-1999 Karolinska Institutet Post-doctoral fellow

1999-2013 Karolinska Institutet Associate Professor in Molecular Medicine

2013- Karolinska Institutet Professor in Immunotherapy in Neuroinflammation

7. Scientific Record

10 selected publications from a total of 70 published scientific papers and 1 review:

Abdul-Majid KB, Jirholt J, Stadelmann C, Stefferl A, Kjellen P, Wallstrom E, Holmdahl R, Lassmann H, Olsson T, Harris RA: Screening of several H-2 congenic mouse strains identified H-2(q) mice as highly susceptible to MOG-induced EAE with minimal adjuvant requirement. J Neuroimmunol 2000;111:23-33. PMID: 11063818

Achour A, Michaelsson J, Harris RA, Odeberg J, Grufman P, Sandberg JK, Levitsky V, Karre K, Sandalova T, Schneider G: A structural basis for LCMV immune evasion: subversion of H-2D(b) and H-2K(b) presentation of gp33 revealed by comparative crystal structure.Analyses. Immunity 2002;17:757-768. PMID: 12479822

Wallberg M, Wefer J, Harris RA: Vaccination with myelin oligodendrocyte glycoprotein adsorbed to alum effectively protects DBA/1 mice from experimental autoimmune encephalomyelitis. Eur J Immunol 2003;33:1539-1547. PMID: 12778471

Andersson A, Kokkola R, Wefer J, Erlandsson-Harris H, Harris RA: Differential macrophage expression of IL-12 and IL-23 upon innate immune activation defines rat autoimmune susceptibility. J Leukoc Biol 2004;76:1118-1124. PMID: 15371491

Wallberg M, Harris RA: Co-infection with Trypanosoma brucei brucei prevents experimental autoimmune encephalomyelitis in DBA/1 mice through induction of suppressor APCs. Int Immunol 2005;17:721-728. PMID: 15899926

Wallberg M, Bergquist J, Achour A, Breij E, Harris RA: Malondialdehyde modification of myelin oligodendrocyte glycoprotein leads to increased immunogenicity and encephalitogenicity. Eur J Immunol 2007;37:1986-1995. PMID: 17523133

Steed J, Gilliam LK, Harris RA, Lernmark A, Hampe CS: Antigen presentation of detergent-free glutamate decarboxylase (GAD65) is affected by human serum albumin as carrier protein. J Immunol Methods 2008;334:114-121. PMID: 18353353

Thessen Hedreul M, Gillett A, Olsson T, Jagodic M, Harris RA: Characterization of Multiple Sclerosis candidate gene expression kinetics in rat experimental autoimmune encephalomyelitis. J Neuroimmunol 2009;210:30-39. PMID: 19269041

Parsa R., Andresen P., Gillett A., Mia S., Zhang X-M., Mayans S., Holmberg D., Harris RA. Adoptive Transfer of Immunomodulatory M2 Macrophages Prevents Type 1 Diabetes in NOD Mice. Diabetes 2012, 61:2881-92; PMID: 22745325

Harris RA, Amor S: Sweet and sour – oxidative and carbonyl stress in neurological disorders. CNS Neurol Disorders – Drug Targets 2010 10(1):82-107. PMID:21143140

8. Doctoral Education Record

2005-10 – present Director of Doctoral Education (part-time)

Dept of Clinical Neurosciences, Karolinska Institutet

2008-09 – present Central Director of Doctoral Education (part-time)

Central Administration, Karolinska Institutet

Ph.D examiner 7 times nationally/internationally

Lic. examiner 1 time

Ph.D exam committee member 18 times

Licentiate exam committee member 10 times

Ph.D half-time control committee member 26 times

Examiner for Docentur 2 times

Supervised 4 PhD students as main supervisor and 14 PhD students as co-supervisor

Currently supervise 5 PhD students as main supervisor and 4 PhD students as co-supervisor

9. Commissions of Trust Record

Grant/Position reviewer for: Multiple Sclerosis UK, Diabetes UK, Dutch MS Research Foundation, Wellcome Trust, Stockholm University, Karolinska Instititet; all 2003-

Editor: Frontiers in Molecular Innate Immunology 2010-

Ad hoc reviewer for scientific journals: Fronteirs in Molecular Innate Immunology; Acta Neurobiologiae Experimentalis; Scandanavian Journal of Immunology; Faseb Journal; Headache; European Journal of Neurology; European Journal of Neuroinflammation; BMC Immunology; Cellular Physiology and Biochemistry; Neuroimmunomodulation; PNAS; International Immunology; International Journal of Neuropsychopharmacology; European Journal of Immunology; Immunology; European Journal of Immunology; Journal of Neuropathology & Experimental Neurology; Acta Tropica; Journal of Neuroimmunology; Vaccine

10. Membership of Professional Organisations

Society for Neuroimmunology

Society for Leukocyte Biology

European Macrophage and Dendritic Cell Society

11. Membership of Boards

2000-2009 Member of the steering board for the Allergy, Inflammation & Immunology doctoral education programme at Karolinska Institutet.

2002-2005 Member of the steering board of the Junior Faculty, Karolinska Institutet.

2003-present Member of Departmental Board at Karolinska Institutet.

2004-2010 Member of Stockholm North animal ethical Board.

2005-2009 Member of the steering board for the Neurosciences doctoral education programme at Karolinska Institutet.

2005-2010 Member of the steering board for the immunology & inflammation network (KiiM) at Karolinska Institutet.

2008-present Teacher representative within KI Board of Doctoral Education.

2010-present Member of Kvalitetsråd at Karolinska Institutet.

2012-present Executive Committee Member ORPHEUS (Organisation of PhD Education in Biomedicine and Health Sciences in the European System).

2012-present Member of Central Experimental Animal steering Board at Karolinska Institutet.

12. Academic distinctions

Wellcome Trust Travel Fellow award recipient 1994-1996
British Council Visiting Professor award recipient 1995